Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 12/20 | 0.43 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | PLAU | P00749 | 5/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | PROC | P04070 | 2/20 | 0.39 |
| ▸ | HPN | P05981 | 3/20 | 0.38 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7584788 | 0.99 | PLG (0.43) | PLGF10PLAUST14F2 | |
| SCHEMBL7589186 | 0.85 | PKM (0.41) | PLGF10PLAUST14F2 | |
| SCHEMBL7058121 | 0.75 | PLG (0.43) | PLGF10PLAUST14F2 | |
| SCHEMBL29584308 | 0.66 | SLC7A5 (0.65) | PKM | |
| SCHEMBL93303 | 0.66 | SLC7A5 (0.65) | PKM | |
| SCHEMBL93304 | 0.66 | SLC7A5 (0.65) | PKM | |
| SCHEMBL29554654 | 0.66 | SLC7A5 (0.65) | PKM | |
| SCHEMBL837890 | 0.66 | SLC7A5 (0.65) | PKM | |
| SCHEMBL29401985 | 0.66 | SLC7A5 (0.65) | PKM | |
| SCHEMBL29375097 | 0.66 | SLC7A5 (0.65) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635008-B1 | PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS | PENTAPHARM AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| US-5607937-A | Piperazides of substituted phenylalanine derivatives as thrombin inhibitors | PENTAPHARM AG (CH) | 1997-03-04 | — | — | US | disclosed |