SCHEMBL75892

SCHEMBL75892

c1ccc(-c2c(Nc3nc(Nc4ccc5ccccc5c4-c4ccccc4)nc(Nc4ccc5ccccc5c4-c4ccccc4)n3)ccc3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 3/20 0.39
TP53 P04637 2/20 0.39
ATM Q13315 2/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
CDC25B P30305 1/20 0.39
CCR4 P51679 1/20 0.39
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
TDP1 Q9NUW8 2/20 0.38
CYP2A6 P11509 1/20 0.38
WDR5 P61964 1/20 0.38
MAPT P10636 7/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11848196 0.84 ALDH1A1 (0.58) ALDH1A1TSHRHSD17B10HPGDTP53
SCHEMBL31243247 0.84 ALDH1A1 (0.58) ALDH1A1TSHRHSD17B10HPGDTP53
SCHEMBL31321397 0.82 CYP3A4 (0.56) ALDH1A1TSHRHSD17B10HPGDTP53
SCHEMBL24553526 0.81 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10HPGDTP53
SCHEMBL31321400 0.81 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10HPGDTP53
SCHEMBL31303820 0.81 ALDH1A1 (0.55) ALDH1A1TSHRHSD17B10HPGDTP53
SCHEMBL25125677 0.79 CDC25B (0.48) ALDH1A1TSHRHSD17B10HPGDTP53
SCHEMBL31321396 0.78 ALDH1A1 (0.53) ALDH1A1TSHRHSD17B10HPGDTP53
SCHEMBL2801565 0.78 MAPT (0.41) ALDH1A1TSHRHSD17B10HPGDTP53
SCHEMBL2803560 0.77 GAA (0.48) ALDH1A1TSHRHSD17B10HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110240965-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-10-06 US claimed
US-7776457-B2 A OLED layer composed of phosphorescent dopant disposed between a first electrode and a second electrode; and a blue light emitting layer contacting the light emitting layer, wherein the light emitting layer has a hole transport material and an electron transport material as a host SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-08-17 US claimed
US-7597967-B2 Phosphorescent OLEDs with exciton blocking layer EASTMAN KODAK COMPANY (US) 2009-10-06 US claimed
EP-1701394-A1 Organic electroluminescent device and method of manufacturing the same Samsung SDI Co., Ltd. (KR) 2006-09-13 EP claimed
US-20060199038-A1 Organic electroluminescent device and method of manufacturing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2006-09-07 US claimed
US-20060134461-A1 Organometallic materials and electroluminescent devices EASTMAN KODAK COMPANY 2006-06-22 US claimed
US-20060134460-A1 Phosphorescent oleds with exciton blocking layer GLOBAL OLED TECHNOLOGY LLC 2006-06-22 US claimed
US-20060105201-A1 Organic electroluminescent device SAMSUNG DISPLAY CO., LTD. (KR) 2006-05-18 US claimed
US-20050287393-A1 Organic electroluminescent device SAMSUNG SDI CO., LTD. (KR) 2005-12-29 US claimed
EP-1610398-A2 Organic electroluminescent device Samsung SDI Co., Ltd. (KR) 2005-12-28 EP claimed
EP-3211056-B1 COMPOUNDS FOR USE IN OPTO-ELECTRICAL DEVICES CDT OXFORD LTD (GB) 2020-07-22 EP disclosed
EP-2984079-B1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LTD (GB) 2020-07-01 EP disclosed
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices POWER OLEDS LIMITED (GB) 2019-10-08 US disclosed
EP-2243177-B1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS GLOBAL OLED TECHNOLOGY LLC (US) 2019-05-15 EP disclosed
US-20180323378-A9 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LIMITED (GB) 2018-11-08 US disclosed
US-20060134461-A1 Organometallic materials and electroluminescent devices EASTMAN KODAK COMPANY 2006-06-22 US disclosed
US-20060134460-A1 Phosphorescent oleds with exciton blocking layer GLOBAL OLED TECHNOLOGY LLC 2006-06-22 US disclosed
US-20060105201-A1 Organic electroluminescent device SAMSUNG DISPLAY CO., LTD. (KR) 2006-05-18 US disclosed
US-20050287393-A1 Organic electroluminescent device SAMSUNG SDI CO., LTD. (KR) 2005-12-29 US disclosed
EP-1610398-A2 Organic electroluminescent device Samsung SDI Co., Ltd. (KR) 2005-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180323378-A9 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES NAT1, SLCO2A1, SLCO2B1 THRB 1884/4885ALDH1A1 789/4885TSHR 1859/4885
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices NAT1, SLCO2A1, SLCO2B1 THRB 1884/4885ALDH1A1 789/4885TSHR 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.