Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585422 | 0.87 | ESR1 (0.48) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL7590331 | 0.87 | ESR1 (0.41) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL7592604 | 0.87 | ESR1 (0.51) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL7585426 | 0.82 | ESR1 (0.45) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL7592611 | 0.81 | ESR1 (0.46) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL5855310 | 0.81 | ESR1 (0.39) | ESR1ESR2PPARG | |
| SCHEMBL7587953 | 0.80 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL7589642 | 0.79 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL24103707 | 0.77 | ESR1 (0.55) | ESR1ESR2 | |
| SCHEMBL17965956 | 0.77 | ESR1 (0.55) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |
| EP-0944613-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C Research Laboratories (KR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025916-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1998-06-18 | — | — | WO | disclosed |