Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 11/20 | 0.35 |
| ▸ | PPARD | Q03181 | 11/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589244 | 0.87 | ESR1 (0.49) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL5857617 | 0.85 | PPARG (0.33) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL7588340 | 0.84 | ESR1 (0.47) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL7589458 | 0.84 | ESR1 (0.46) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL7587424 | 0.80 | ESR1 (0.32) | ESR1ESR2PPARGPPARDPGR | |
| SCHEMBL8519738 | 0.77 | ESR1 (0.42) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL7589620 | 0.76 | ESR1 (0.31) | ESR1 | |
| SCHEMBL8520859 | 0.75 | PPARG (0.30) | ESR1PPARGPPARD | |
| SCHEMBL7585422 | 0.74 | ESR1 (0.48) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL7592604 | 0.74 | ESR1 (0.51) | ESR1ESR2PPARGPPARDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |
| EP-0944613-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C Research Laboratories (KR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025916-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1998-06-18 | — | — | WO | disclosed |