Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409299 | 1.00 | TSHR (0.62) | TSHRALDH1A1LMNAALOX15SIGMAR1 | |
| SCHEMBL81026 | 0.89 | TSHR (0.59) | TSHRALDH1A1LMNAALOX15SIGMAR1 | |
| SCHEMBL94846 | 0.85 | TSHR (0.67) | TSHRALDH1A1LMNAALOX15TRPV1 | |
| SCHEMBL30036663 | 0.85 | TSHR (0.67) | TSHRALDH1A1LMNAALOX15TRPV1 | |
| SCHEMBL30409059 | 0.84 | TSHR (0.53) | TSHRALDH1A1LMNAALOX15SIGMAR1 | |
| SCHEMBL21647739 | 0.84 | TSHR (0.53) | TSHRALDH1A1LMNAALOX15SIGMAR1 | |
| SCHEMBL28275071 | 0.84 | TSHR (0.61) | TSHRALDH1A1LMNAALOX15TRPV1 | |
| SCHEMBL15921150 | 0.83 | TSHR (0.65) | TSHRALDH1A1LMNASIGMAR1CYP1A2 | |
| SCHEMBL7399400 | 0.83 | TSHR (0.65) | TSHRALDH1A1LMNAALOX15SIGMAR1 | |
| SCHEMBL10490768 | 0.83 | TSHR (0.65) | TSHRALDH1A1LMNAALOX15TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486115-B1 | ELECTRORHEOLOGIC FLUID COMPRISING ORGANIC SUBSTANCES THAT CAN BE DOPED AND USE THEREOF | FRAUNHOFER GES FORSCHUNG (DE) | 2015-05-20 | — | — | EP | claimed |
| EP-2486115-A1 | ELECTRORHEOLOGICAL FLUID COMPRISING ORGANIC DOPANTS, AND USE THEREOF | Fraunhofer Gesellschaft zur Förderung der angewandten Wissenschaft E.V. (DE) | 2012-08-15 | — | — | EP | claimed |
| WO-2011042117-A1 | ELECTRORHEOLOGICAL FLUID COMPRISING ORGANIC DOPANTS, AND USE THEREOF | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2011-04-14 | — | — | WO | claimed |
| US-20250188023-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-06-12 | — | — | US | disclosed |
| US-12258308-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-03-25 | — | — | US | disclosed |
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |
| CN-112513011-B | Benzene derivatives | 小野药品工业株式会社 | 2023-06-16 | — | — | CN | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| US-11289238-B2 | Compositions for the filling of high aspect ratio vertical interconnect access (VIA) holes | HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC (US) | 2022-03-29 | — | — | US | disclosed |
| US-20220089532-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-24 | — | — | US | disclosed |
| US-4801710-A | Regioselective synthesis of 9-substituted purine acyclonucleoside derivatives | MERCK & CO., INC. (US) | 1989-01-31 | — | — | US | disclosed |
| US-4752621-A | Arylalkyl amines useful for lowering intraocular pressure | SYNTEX (U.S.A.) INC. (US) | 1988-06-21 | — | — | US | disclosed |
| US-4683234-A | HYPOTENSIVE AGENTS, ANTI-ANGINA | SUNTORY LIMITED (JP) | 1987-07-28 | — | — | US | disclosed |
| EP-0212375-A1 | Moderated reduction reactions for producing arylhydroxylamines | MicroSi, Inc. (a Delaware corporation) (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4642378-A | Arylalkyl amines useful for lowering intraocular pressure | SYNTEX (U.S.A.) INC. (US) | 1987-02-10 | — | — | US | disclosed |
| US-4629730-A | ADMINISTERING DIALKYL OR CYCLOAKYL AMINO ETHYLANILINE DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1986-12-16 | — | — | US | disclosed |
| EP-0184473-A1 | Regioselective synthesis of 9-substituted purine acyclonucleoside derivatives | MERCK & CO. INC. (US) | 1986-06-11 | — | — | EP | disclosed |
| EP-0180994-A2 | Antihypertensive dialkyl aminoethylaniline derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-05-14 | — | — | EP | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12258308-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | TSHR 4497/4885ALDH1A1 1189/4885LMNA 1367/4885 |
| US-20250188023-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | TSHR 4501/4885ALDH1A1 1203/4885LMNA 1430/4885 |
| US-20220089532-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | TSHR 4497/4885ALDH1A1 1189/4885LMNA 1367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.