Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | MARS1 | P56192 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929995 | 1.00 | SRD5A2 (0.43) | SRD5A2EDNRBEDNRAAHRMARS1 | |
| SCHEMBL6929961 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL6929228 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL7567210 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL7567255 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL6026250 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL6933173 | 0.79 | AHR (0.41) | AHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7591786 | 0.79 | AHR (0.41) | AHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL6930001 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL6931344 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246811-A1 | METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES | OXIS Isle of Man, Limited (GB) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049671-A1 | METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES | OXIS ISLE OF MAN, LIMITED (US) | 2001-07-12 | — | — | WO | disclosed |