Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PGD | P52209 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592880 | 0.97 | POLB (0.42) | POLBMAPK1TDP1PGDABCB1 | |
| SCHEMBL7592065 | 0.86 | POLB (0.36) | POLBMAPK1TDP1PGD | |
| SCHEMBL7595386 | 0.85 | POLB (0.35) | POLBMAPK1TDP1PGDABCB1 | |
| SCHEMBL3026389 | 0.82 | POLB (0.42) | POLBMAPK1TDP1PGDABCB1 | |
| SCHEMBL3024742 | 0.79 | POLB (0.40) | POLBMAPK1TDP1PGD | |
| SCHEMBL6228292 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL7592606 | 0.75 | LMNA (0.37) | POLBMAPK1TDP1 | |
| SCHEMBL6228009 | 0.75 | LMNA (0.44) | — | |
| SCHEMBL3029790 | 0.74 | POLB (0.36) | POLBMAPK1TDP1PGD | |
| SCHEMBL7591433 | 0.72 | LMNA (0.33) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |