Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.54 |
| ▸ | POLB | P06746 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595302 | 0.89 | ALDH1A1 (0.45) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL1641498 | 0.85 | TSHR (0.56) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL8186141 | 0.84 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL11334227 | 0.83 | ALDH1A1 (0.58) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL9190764 | 0.83 | POLB (0.55) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL1532451 | 0.80 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL8440662 | 0.80 | ALDH1A1 (0.60) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL28653248 | 0.78 | TSHR (0.52) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL6130008 | 0.77 | ALDH1A1 (0.57) | ALDH1A1POLBMAPTTDP1HPGD | |
| SCHEMBL456021 | 0.77 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811618-B1 | Furfurylthioalkanes, process for their preparation and use thereof | HAARMANN & REIMER GMBH (DE) | 2002-10-23 | — | — | EP | claimed |
| US-6153770-A | ORGANOLEPTIC COMPOUNDS FOR FOOD AROMAS | HAARMANN & REIMER (DE) | 2000-11-28 | — | — | US | claimed |
| EP-0811618-A1 | Furfurylthioalkanes, process for their preparation and use thereof | HAARMANN & REIMER GMBH (DE) | 1997-12-10 | — | — | EP | claimed |
| EP-0811618-B1 | Furfurylthioalkanes, process for their preparation and use thereof | HAARMANN & REIMER GMBH (DE) | 2002-10-23 | — | — | EP | disclosed |
| US-6153770-A | ORGANOLEPTIC COMPOUNDS FOR FOOD AROMAS | HAARMANN & REIMER (DE) | 2000-11-28 | — | — | US | disclosed |
| EP-0811618-A1 | Furfurylthioalkanes, process for their preparation and use thereof | HAARMANN & REIMER GMBH (DE) | 1997-12-10 | — | — | EP | disclosed |