SCHEMBL759008

SCHEMBL759008

C=CC(O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
BLM P54132 2/20 0.41
ALOX15 P16050 1/20 0.41
PMP22 Q01453 1/20 0.41
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
CA2 P00918 5/20 0.38
CA1 P00915 4/20 0.38
L3MBTL1 Q9Y468 1/20 0.35
FOLH1 Q04609 2/20 0.35
RIMKLA Q8IXN7 1/20 0.35
NAALAD2 Q9Y3Q0 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MEN1 O00255 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1843782 1.00 KMT2A (0.41) KMT2ABLMALOX15PMP22MMP2
SCHEMBL10355085 0.86 FOLH1 (0.50) KMT2ABLMFOLH1RIMKLANAALAD2
SCHEMBL20154874 0.86 FOLH1 (0.50) KMT2ABLMFOLH1RIMKLANAALAD2
SCHEMBL757317 0.82 ECE1 (0.40) KMT2ACA2CA1MEN1TGFBR1
SCHEMBL24165071 0.80 KMT2A (0.48) KMT2ABLMALOX15PMP22MMP2
Phosphoric Acid SCHEMBL27542272 0.78 KMT2A (0.41) KMT2ABLMALOX15PMP22MMP2
SCHEMBL3083186 0.78 CA2 (0.40) KMT2ABLMALOX15PMP22MMP2
SCHEMBL3083184 0.78 CA2 (0.40) KMT2ABLMALOX15PMP22MMP2
SCHEMBL3334377 0.77 KMT2A (0.45) KMT2ABLMALOX15PMP22MMP2
SCHEMBL18680610 0.77 KMT2A (0.45) KMT2ABLMALOX15PMP22MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248696-A1 LENALIDOMIDE PRODRUGS, POLYMERIC CONJUGATES, AND FORMULATIONS THEREOF, AND THEIR USES FOR THE TREATMENT OF MULTIPLE MYELOMA DYNAMIC BIOLOGICS INC (US) 2023-08-10 US claimed
EP-3989939-A1 LEVODOPA POLYMERIC CONJUGATES, FORMULATIONS THEREOF, AND THEIR USES FOR THE TREATMENT OF PARKINSON'S DISEASE Dynamic Biologics Inc. (US) 2022-05-04 EP claimed
US-10952970-B2 Use of vitelline protein B as a microencapsulating additive THE TEXAS A&M UNIVERSITY SYSTEM (US) 2021-03-23 US claimed
WO-2020264460-A1 LEVODOPA POLYMERIC CONJUGATES, FORMULATIONS THEREOF, AND THEIR USES FOR THE TREATMENT OF PARKINSON'S DISEASE DYNAMIC BIOLOGICS INC. (US) 2020-12-30 WO claimed
WO-2020227183-A1 LENALIDOMIDE PRODRUGS, POLYMERIC CONJUGATES, AND FORMULATIONS THEREOF, AND THEIR USES FOR THE TREATMENT OF MULTIPLE MYELOMA DYNAMIC BIOLOGICS INC. (US) 2020-11-12 WO claimed
WO-2020081116-A1 POLYMERIC COMPOUNDS AND COMPOSITIONS OF FUMARIC ACID ESTERS AND THEIR USE IN TREATING RELAPSING–REMITTING MULTIPLE SCLEROSIS AND PSORIASIS DYNAMIC BIOLOGICS INC. (US) 2020-04-23 WO claimed
US-20170135958-A1 Use of Vitelline Protein B as a Microencapsulating Additive THE UNIVERSITY OF DELAWARE 2017-05-18 US claimed
US-9522120-B2 Compositions and methods of making sustained release liquid formulations NEOS THERAPEUTICS, LP (US) 2016-12-20 US claimed
US-9387279-B2 Implantable-glucose responsive insulin delivery device THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2016-07-12 US claimed
US-20130084340-A1 Compositions and Methods of Making Sustained Release Liquid Formulations NEOS THERAPEUTICS, LP (US) 2013-04-04 US claimed
EP-2164631-A1 MODIFYING DRUG RELEASE IN SUSPENSIONS OF IONIC RESIN SYSTEMS Neos Therapeutics, LP (US) 2010-03-24 EP claimed
WO-2009037313-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS NIRVANA'S TREE HOUSE B.V. (NL) 2009-03-26 WO claimed
US-20090011027-A1 Modifying Drug Release in Suspensions of Ionic Resin Systems NEOS THERAPEUTICS, LP (US) 2009-01-08 US claimed
WO-2008151071-A1 MODIFYING DRUG RELEASE IN SUSPENSIONS OF IONIC RESIN SYSTEMS NEOS THERAPEUTICS, LP (US) 2008-12-11 WO claimed
US-20060193877-A1 Compositions and methods of making sustained release liquid formulations PFAB, LP (US) 2006-08-31 US claimed
US-20050260258-A1 Use of vitelline protein B as a microencapsulating additive THE TEXAS A&M UNIVERSITY SYSTEM (US) 2005-11-24 US claimed
US-6565872-B2 A composite polymer system comprising a stimuli-responsive polymer selected from R-acrylamide, R1-acryalate, R2-acrylic acid, polyethylene glycol(R,R1,R2=H or alkyl) at least one second polymer such as, polysaccharide, cellulose, polyester Wu, Xiao Yu (CA) 2003-05-20 US claimed
EP-0245820-B1 Biodegradable microspheres as a carrier for macromolecules UNIV KENTUCKY RES FOUND (US) 1995-12-27 EP claimed
US-5160745-A Three dimensional network, sustained release of hormones, peptides, vaccines, enzymes THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1992-11-03 US claimed
US-4741872-A Preparation of biodegradable microspheres useful as carriers for macromolecules THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1988-05-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248696-A1 LENALIDOMIDE PRODRUGS, POLYMERIC CONJUGATES, AND FORMULATIONS THEREOF, AND THEIR USES FOR THE TREATMENT OF MULTIPLE MYELOMA MALT1, BCL6, BCR KMT2A 299/4885BLM 4599/4885ALOX15 1607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.