Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590242 | 1.00 | PTGES2 (0.57) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL6832043 | 0.83 | L3MBTL1 (0.54) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL1123001 | 0.80 | KMT2A (0.71) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL1122377 | 0.77 | PTGES2 (0.70) | PTGES2ALDH1A1HTT | |
| SCHEMBL827960 | 0.76 | KMT2A (0.62) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL827959 | 0.76 | KMT2A (0.62) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL6861188 | 0.75 | KMT2A (0.60) | ALDH1A1KMT2APPARGPOLBKDM4E | |
| SCHEMBL6861189 | 0.75 | KMT2A (0.60) | ALDH1A1KMT2APPARGPOLBKDM4E | |
| SCHEMBL13510446 | 0.73 | EP300 (0.53) | PTGES2ALDH1A1HTTKMT2APKM | |
| SCHEMBL1122431 | 0.73 | KMT2A (0.77) | PTGES2ALDH1A1HTTKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |