Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813333 | 0.78 | — | — | |
| SCHEMBL8006443 | 0.75 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL6839583 | 0.74 | CRHR1 (0.30) | CRHR1 | |
| SCHEMBL7806586 | 0.74 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL22833928 | 0.73 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL29501666 | 0.73 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL7806584 | 0.72 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL29873429 | 0.72 | KMT2A (0.38) | CRHR1 | |
| SCHEMBL22855416 | 0.72 | KMT2A (0.38) | CRHR1 | |
| SCHEMBL22855428 | 0.70 | CRHR1 (0.41) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812831-B1 | Benzimidazole derivatives and their use as corticotropin releasing factor antagonists | PFIZER (US) | 2002-09-04 | — | — | EP | disclosed |
| US-6022978-A | Benzimidazole derivatives | PFIZER INC. (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0812831-A1 | Benzimidazole derivatives and their use as corticotropin releasing factor antagonists | PFIZER INC. (US) | 1997-12-17 | — | — | EP | disclosed |