Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.64 |
| ▸ | AR | P10275 | 5/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870568 | 0.86 | PGR (0.69) | PGRARNR3C1NR3C2 | |
| SCHEMBL4167996 | 0.83 | PGR (0.65) | PGRARNR3C1NR3C2 | |
| SCHEMBL3876795 | 0.81 | PGR (0.62) | PGRARNR3C1NR3C2 | |
| SCHEMBL3869121 | 0.79 | PGR (0.60) | PGRARNR3C1NR3C2 | |
| SCHEMBL3870140 | 0.78 | PGR (1.00) | PGRARNR3C1NR3C2 | |
| SCHEMBL3872257 | 0.76 | PGR (1.00) | PGRARNR3C1NR3C2 | |
| SCHEMBL3876807 | 0.76 | PGR (0.65) | PGRARNR3C1NR3C2 | |
| SCHEMBL3869124 | 0.73 | PGR (0.69) | PGRARNR3C1NR3C2 | |
| SCHEMBL3883683 | 0.73 | PGR (0.86) | PGRARNR3C1NR3C2 | |
| SCHEMBL3870802 | 0.72 | PGR (1.00) | PGRARNR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173426-A1 | CYCLOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066571-A1 | CYCLOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |