Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13138908 | 0.87 | LMNA (0.62) | LMNACYP2C19HIF1ASMN1; SMN2TYMP | |
| SCHEMBL13885446 | 0.87 | LMNA (0.65) | LMNACYP2C19HIF1ASMN1; SMN2TYMP | |
| SCHEMBL8663593 | 0.86 | LMNA (0.61) | LMNACYP2C19HIF1ASMN1; SMN2TYMP | |
| SCHEMBL10044866 | 0.85 | LMNA (0.58) | LMNACYP2C19HIF1A | |
| SCHEMBL9976300 | 0.85 | LMNA (0.60) | LMNACYP2C19HIF1ASMN1; SMN2TYMP | |
| SCHEMBL13247559 | 0.85 | LMNA (0.60) | LMNACYP2C19HIF1ASMN1; SMN2TYMP | |
| SCHEMBL7592553 | 0.85 | LMNA (0.57) | LMNACYP2C19HIF1ASMN1; SMN2TYMP | |
| SCHEMBL12871758 | 0.84 | LMNA (0.64) | LMNACYP2C19HIF1ASMN1; SMN2TYMP | |
| SCHEMBL13247491 | 0.84 | LMNA (0.61) | LMNACYP2C19HIF1ASMN1; SMN2TYMP | |
| SCHEMBL13246453 | 0.84 | LMNA (0.61) | LMNACYP2C19HIF1ASMN1; SMN2TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |