Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27692266 | 0.98 | KEAP1 (0.39) | KEAP1NFE2L2EPHX1ZDHHC7MEN1 | |
| SCHEMBL27877359 | 0.92 | KEAP1 (0.46) | KEAP1NFE2L2EPHX1MEN1KMT2A | |
| SCHEMBL21051000 | 0.92 | KEAP1 (0.46) | KEAP1NFE2L2EPHX1MEN1KMT2A | |
| SCHEMBL27710862 | 0.90 | KEAP1 (0.45) | KEAP1NFE2L2EPHX1MEN1KMT2A | |
| SCHEMBL28570325 | 0.84 | KEAP1 (0.45) | KEAP1NFE2L2CYP2C19 | |
| SCHEMBL28359053 | 0.83 | KEAP1 (0.50) | KEAP1NFE2L2EPHX1 | |
| SCHEMBL20897828 | 0.83 | KEAP1 (0.50) | KEAP1NFE2L2EPHX1 | |
| SCHEMBL20897312 | 0.83 | KEAP1 (0.50) | KEAP1NFE2L2EPHX1 | |
| SCHEMBL31122197 | 0.83 | KEAP1 (0.50) | KEAP1NFE2L2EPHX1 | |
| SCHEMBL28883654 | 0.83 | KEAP1 (0.50) | KEAP1NFE2L2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482779-B2 | SYNTHETIC OIL AS A BASE OIL, LITHIUM SOAP THICKENER, ADDITIVE SELECTED FROM ORGANIC MOLYBDENUM COMPOUND, ORGANIC FATTY ACID COMPOUND OR A DERIVATIVE THEREOF, ORGANIC PHOSPHORUS COMPOUND | NSK LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| US-20020002119-A1 | Lubricating grease composition and rolling apparatus comprising same | NSK LTD. (JP) | 2002-01-03 | — | — | US | disclosed |
| EP-1136545-A2 | Lubricating grease composition and rolling apparatus comprising same | NSK LTD (JP) | 2001-09-26 | — | — | EP | disclosed |