Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952562 | 0.72 | ELANE (1.00) | ELANEKDM4EPKMCYP2C19SMN1; SMN2 | |
| SCHEMBL19923423 | 0.70 | ELANE (0.61) | ELANESMN1; SMN2 | |
| SCHEMBL11800500 | 0.69 | ELANE (0.42) | ELANECYP2C19NPC1GAA | |
| SCHEMBL11790893 | 0.68 | ELANE (0.45) | ELANEKDM4EPKMALDH1A1GAA | |
| SCHEMBL19923441 | 0.68 | GRM4 (0.57) | ELANEALDH1A1GAA | |
| SCHEMBL9457060 | 0.68 | KDM4E (0.61) | ELANEKDM4EPKMCYP2C19SMN1; SMN2 | |
| SCHEMBL9726893 | 0.68 | ELANE (0.49) | ELANEKDM4EPKMCYP2C19SMN1; SMN2 | |
| SCHEMBL19693968 | 0.68 | ELANE (0.43) | ELANEKDM4EPKMLMNAMEN1 | |
| SCHEMBL19923452 | 0.67 | ELANE (0.56) | ELANECYP2C19SMN1; SMN2LMNAMEN1 | |
| SCHEMBL19923463 | 0.66 | ELANE (0.46) | ELANESMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593956-B1 | Agglutination assays using multivalent ligands | DADE BEHRING INC (US) | 2002-02-13 | — | — | EP | disclosed |
| US-5401636-A | Enhanced sensitivity agglutination assays multivalent ligands | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0593956-A2 | Agglutination assays using multivalent ligands | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-27 | — | — | EP | disclosed |