Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865451 | 0.81 | ELANE (0.51) | ELANEALDH1A1CYP2C19MAPK1 | |
| SCHEMBL9180362 | 0.70 | ELANE (0.43) | ELANEKDM4EPKMMEN1GAA | |
| SCHEMBL28024212 | 0.69 | ALDH1A1 (0.41) | ALOX12ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL7590658 | 0.68 | ELANE (0.56) | ELANEKDM4EPKMMEN1GAA | |
| SCHEMBL10952562 | 0.66 | ELANE (1.00) | ELANEKDM4EPKMMEN1KMT2A | |
| SCHEMBL16867650 | 0.66 | ELANE (0.43) | ELANEKDM4EMEN1GAAKMT2A | |
| SCHEMBL11774175 | 0.66 | ELANE (0.50) | ELANEMEN1GAAALOX12KMT2A | |
| SCHEMBL9457060 | 0.65 | KDM4E (0.61) | ELANEKDM4EPKMMEN1GAA | |
| SCHEMBL16865402 | 0.65 | ELANE (0.48) | ELANEPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL3546835 | 0.65 | KDM4E (0.50) | ELANEKDM4EPKMMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4225965-A | — | — | None | — | — | JP | disclosed |
| JP-H04225965-A | INSECTICIDAL BARBITURIC ACID DERIVATIVE, ITS PREPARATION AND INSECTICIDAL COMPOSITION CONTAINING IT AS ACTIVE INGREDIENT | DUPHAR INTERNATL RES BV | 1992-08-14 | — | — | JP | disclosed |