Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030922 | 0.91 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL10624509 | 0.91 | LMNA (0.57) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9352754 | 0.89 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL14087041 | 0.89 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL7594162 | 0.88 | LMNA (0.50) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL7592858 | 0.87 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL23817080 | 0.87 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8375526 | 0.87 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9188727 | 0.87 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3067086 | 0.87 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| US-5993780-A | A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE | NYCOMED IMAGING AS (NO) | 1999-11-30 | — | — | US | disclosed |
| US-5958376-A | Iodinated X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| US-5958375-A | Urea-linked, iodinated bis phenyl compounds for X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| EP-0782565-B1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-04-07 | — | — | EP | disclosed |
| CN-1164225-A | Iodinated X-ray-contrast media | NYCOMED IMAGING AS (NO) | 1997-11-05 | — | — | CN | disclosed |