SCHEMBL7590915

SCHEMBL7590915

CCCC1CCCC(CCC)C1[Si](Cl)(Cl)Cl

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
ADRA2A P08913 2/20 0.33
ADRA2B P18089 2/20 0.33
ADRA2C P18825 2/20 0.33
ADRA1A P35348 1/20 0.33
NOS1 P29475 3/20 0.31
NOS2 P35228 3/20 0.31
NOS3 P29474 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7599365 0.94 CA1 (0.41) CA1CA2CA4ADRA2AADRA2B
SCHEMBL7595030 0.91 CA1 (0.38) CA1CA2CA4NOS1NOS2
SCHEMBL7598354 0.88 CA1 (0.39) CA1CA2CA4ADRA2AADRA2B
SCHEMBL7599113 0.87 CYP1A2 (0.40) CA1CA2CA4NOS1NOS2
SCHEMBL7597043 0.82 CYP1A2 (0.36) CA1CA2CA4NOS1NOS2
SCHEMBL7592469 0.81
SCHEMBL7599353 0.80 CA1 (0.43) CA1CA2CA4ADRA2AADRA2B
SCHEMBL7593041 0.78 NOS1 (0.33) CA1CA2CA4NOS1NOS2
SCHEMBL7593982 0.78 CYP1A2 (0.32) CA1CA2CA4NOS1NOS2
SCHEMBL7594620 0.77 CYP1A2 (0.38) NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894802-B1 Silane compound NIPPON MITSUBISHI OIL CORP (JP) 2002-11-06 EP disclosed
EP-0894802-A2 Silane compound NIPPON OIL CO. LTD. (JP) 1999-02-03 EP disclosed