Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.66 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.66 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.66 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571264 | 0.98 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28571318 | 0.98 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28566974 | 0.98 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7590202 | 0.98 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7591463 | 0.98 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28569758 | 0.98 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7595555 | 0.98 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7597450 | 0.98 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7592525 | 0.95 | ESR1 (0.73) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289821 | 0.93 | ESR1 (0.74) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855400-B1 | Phenylphosphonic acid derivative and production process therefor | NISSAN CHEMICAL IND LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5880309-A | DIALKYL DIALKOXYCARBONYLPHENYL PHOSPHONATES USEFUL AS RESIN MODIFIERS PRODUCED AT HIGH YIELD AND LOW COST BY HEATING A TRIALKYL PHOSPHITE AND A DIALKOXYCARBONYLPHENYL HALIDE IN THE PRESENCE OF A PALLADIUM OR NICKEL CATALYST AND HYDROLYZING | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0855400-A1 | Phenylphosphonic acid derivative and production process therefor | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |