Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.59 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180579 | 0.96 | ESR1 (0.73) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7590980 | 0.95 | ESR1 (0.66) | ESR1TSHRMAPK1AKR1C4AKR1C3 | |
| SCHEMBL7591463 | 0.93 | ESR1 (0.69) | ESR1TSHRLMNAAKR1C4AKR1C3 | |
| SCHEMBL28569758 | 0.93 | ESR1 (0.69) | ESR1TSHRLMNAAKR1C4AKR1C3 | |
| SCHEMBL28571318 | 0.93 | ESR1 (0.69) | ESR1TSHRLMNAAKR1C4AKR1C3 | |
| SCHEMBL7597450 | 0.93 | ESR1 (0.69) | ESR1TSHRLMNAAKR1C4AKR1C3 | |
| SCHEMBL7590202 | 0.93 | ESR1 (0.69) | ESR1TSHRLMNAAKR1C4AKR1C3 | |
| SCHEMBL7595555 | 0.93 | ESR1 (0.69) | ESR1TSHRLMNAAKR1C4AKR1C3 | |
| SCHEMBL28571264 | 0.93 | ESR1 (0.69) | ESR1TSHRLMNAAKR1C4AKR1C3 | |
| SCHEMBL28566974 | 0.93 | ESR1 (0.69) | ESR1TSHRLMNAAKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855400-B1 | Phenylphosphonic acid derivative and production process therefor | NISSAN CHEMICAL IND LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5880309-A | DIALKYL DIALKOXYCARBONYLPHENYL PHOSPHONATES USEFUL AS RESIN MODIFIERS PRODUCED AT HIGH YIELD AND LOW COST BY HEATING A TRIALKYL PHOSPHITE AND A DIALKOXYCARBONYLPHENYL HALIDE IN THE PRESENCE OF A PALLADIUM OR NICKEL CATALYST AND HYDROLYZING | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0855400-A1 | Phenylphosphonic acid derivative and production process therefor | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |