⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569766 | 0.74 | — | — | |
| SCHEMBL853365 | 0.72 | — | — | |
| SCHEMBL8681501 | 0.72 | CA12 (0.35) | — | |
| SCHEMBL9805978 | 0.67 | — | — | |
| SCHEMBL14336269 | 0.67 | — | — | |
| SCHEMBL7168628 | 0.65 | TSHR (0.35) | — | |
| SCHEMBL8914655 | 0.65 | NPC1 (0.30) | — | |
| SCHEMBL857506 | 0.65 | — | — | |
| SCHEMBL584300 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL4814533 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403360-B1 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI SA (FR) | 1996-10-16 | — | — | EP | disclosed |
| EP-0436435-B1 | Phenylethanolaminomethyltetralins, procedure for their preparation and pharmaceutical compositions containing same | SANOFI ELF (FR) | 1994-03-23 | — | — | EP | disclosed |
| EP-0465583-A1 | USE OF A POTASSIC AGONIST IN THE TREATMENT OF GLAUCOMA | ELF SANOFI (FR) | 1992-01-15 | — | — | EP | disclosed |
| EP-0436435-A1 | Phenylethanolaminomethyltetralins, procedure for their preparation and pharmaceutical compositions containing same | ELF SANOFI (FR) | 1991-07-10 | — | — | EP | disclosed |
| EP-0403360-A2 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI (FR) | 1990-12-19 | — | — | EP | disclosed |
| EP-0402203-A2 | Use of a statine derivative for treatment of ophthalmologic disorders | SANOFI (FR) | 1990-12-12 | — | — | EP | disclosed |
| WO-1990011758-A2 | USE OF A POTASSIC AGONIST IN THE TREATMENT OF GLAUCOMA | SANOFI (FR) | 1990-10-18 | — | — | WO | disclosed |