SCHEMBL7591284

SCHEMBL7591284

Cc1ccc(Cc2ccc(NC(=O)c3ccc4c(c3)C(=O)N(C)C4=O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
POLB P06746 6/20 0.55
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 2/20 0.53
HPGD P15428 2/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
GFER P55789 1/20 0.53
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
APP P05067 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
MAPT P10636 1/20 0.51
TSHR P16473 1/20 0.51
MAPK1 P28482 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10098929 0.92 ALDH1A1 (0.62) ALDH1A1POLBHSD17B10KDM4EHPGD
SCHEMBL12960142 0.91 ALDH1A1 (0.66) ALDH1A1POLBHSD17B10KDM4EHPGD
SCHEMBL10098931 0.88 ALDH1A1 (0.58) ALDH1A1POLBHSD17B10KDM4EHPGD
SCHEMBL12446416 0.85 POLB (0.52) ALDH1A1POLBHSD17B10KDM4EHPGD
SCHEMBL7591319 0.85 ALDH1A1 (0.57) ALDH1A1POLBHSD17B10KDM4EHPGD
SCHEMBL24236716 0.83 MEN1 (0.57) ALDH1A1POLBHSD17B10HPGDNPC1
SCHEMBL26431434 0.83 POLB (0.58) ALDH1A1POLBHSD17B10KDM4EHPGD
SCHEMBL15397061 0.82 ALDH1A1 (0.56) ALDH1A1POLBHSD17B10KDM4EHPGD
SCHEMBL15503319 0.82 MEN1 (0.61) ALDH1A1POLBHSD17B10KDM4EHPGD
SCHEMBL13320285 0.80 MEN1 (0.58) ALDH1A1POLBKDM4EHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741441-B2 Insulated wire HITACHI METALS, LTD. (JP) 2014-06-03 US disclosed
US-8642179-B2 Insulating varnish and production method therefor and insulated electric wire using same and production method therefor HITACHI CABLE, LTD. (JP) 2014-02-04 US disclosed
US-8642179-B2 Insulating varnish and production method therefor and insulated electric wire using same and production method therefor HITACHI CABLE, LTD. (JP) 2014-02-04 US disclosed
US-8470913-B2 Thermosetting resin composition and cured product of the same DIC CORPORATION (JP) 2013-06-25 US disclosed
US-20120142829-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT OF THE SAME DIC CORPORATION (JP) 2012-06-07 US disclosed
US-8182155-B2 Lubricating grease and lubricating grease-enclosed roller bearing NTN CORPORATION (JP) 2012-05-22 US disclosed
US-20110198109-A1 INSULATING VARNISH AND PRODUCTION METHOD THEREFOR AND INSULATED ELECTRIC WIRE USING SAME AND PRODUCTION METHOD THEREFOR HITACHI CABLE, LTD. 2011-08-18 US disclosed
US-20110127067-A1 INSULATED WIRE HITACHI CABLE, LTD. (JP) 2011-06-02 US disclosed
US-20100222244-A1 LUBRICATING COMPOSITIONS BASED ON PERFLUOROPOLYETHERS SOLVAY SOLEXIS S.P.A. (IT) 2010-09-02 US disclosed
US-20090232432-A1 Lubricating grease and lubricating grease-enclosed roller bearing NTN CORPORATION (JP) 2009-09-17 US disclosed
US-20070282078-A1 Synthesis of aryl N-acylurea from aryl isocyanates or aryl carbodiimides for use as intermediate in novel sequential self-repetitive reaction (SSRR) to form amides, amide-imides and their polymers NATIONAL CHUNG HSING UNIVERSITY (TW) 2007-12-06 US disclosed