Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2581072 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL14717880 | 0.92 | — | — | |
| SCHEMBL6295540 | 0.91 | — | — | |
| Phenol SCHEMBL7587042 | 0.87 | CA12 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8384472 | 0.85 | GPR3 (0.30) | HTR2A | |
| SCHEMBL8857272 | 0.83 | GPR3 (0.31) | HTR2A | |
| Benzoic Acid SCHEMBL7583824 | 0.81 | DAO (0.39) | — | |
| SCHEMBL8089355 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL8601331 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7645783 | 0.75 | HTR2A (0.30) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743324-B1 | Production of polyethylene using stereoisomeric metallocenes | UNIVATION TECH LLC (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1217013-A2 | Production of polyethylene using stereoisomeric metallocenes | Univation Technologies LLC (US) | 2002-06-26 | — | — | EP | disclosed |
| EP-0743327-B1 | Ethylene polymers having enhanced processability | UNION CARBIDE CHEM PLASTIC (US) | 2001-04-11 | — | — | EP | disclosed |
| US-5852143-A | Production of polyethylene using stereoisomeric metallocenes | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |
| US-5798427-A | EXTRUDABILITY, NARROW COMONOMER DISTRIBUTION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0743327-A2 | Ethylene polymers having enhanced processability | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0743324-A2 | Production of polyethylene using stereoisomeric metallocenes | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |