SCHEMBL7591389

SCHEMBL7591389

CC1=Cc2ccccc2C1[Zr](Cl)(CC=O)(C1C(C)=Cc2ccccc21)=[Si](C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6300381 0.86 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2TDP1
SCHEMBL6300162 0.80
SCHEMBL6300173 0.77
SCHEMBL339225 0.76
SCHEMBL6295664 0.75
SCHEMBL6294758 0.75
SCHEMBL6294753 0.74
SCHEMBL6300012 0.73
SCHEMBL6295531 0.71
SCHEMBL5364828 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743324-B1 Production of polyethylene using stereoisomeric metallocenes UNIVATION TECH LLC (US) 2002-09-11 EP disclosed
EP-1217013-A2 Production of polyethylene using stereoisomeric metallocenes Univation Technologies LLC (US) 2002-06-26 EP disclosed
EP-0743327-B1 Ethylene polymers having enhanced processability UNION CARBIDE CHEM PLASTIC (US) 2001-04-11 EP disclosed
US-5852143-A Production of polyethylene using stereoisomeric metallocenes UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-12-22 US disclosed
US-5798427-A EXTRUDABILITY, NARROW COMONOMER DISTRIBUTION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-08-25 US disclosed
EP-0743327-A2 Ethylene polymers having enhanced processability UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-11-20 EP disclosed
EP-0743324-A2 Production of polyethylene using stereoisomeric metallocenes UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-11-20 EP disclosed