Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590034 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTPOLBRAB9A | |
| SCHEMBL7589790 | 0.80 | TSHR (0.38) | ALDH1A1TSHRMAPTPOLBRAB9A | |
| SCHEMBL7591418 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPTPOLBRAB9A | |
| SCHEMBL7589787 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TSHRMAPTPOLBRAB9A | |
| SCHEMBL10528046 | 0.74 | TSHR (0.46) | ALDH1A1TSHRMAPTPOLBRAB9A | |
| SCHEMBL7589709 | 0.70 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTPOLBRAB9A | |
| SCHEMBL7592515 | 0.68 | TSHR (0.42) | ALDH1A1TSHRMAPTPOLBRAB9A | |
| SCHEMBL11334227 | 0.67 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTPOLBRAB9A | |
| SCHEMBL25385023 | 0.67 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTPOLBRAB9A | |
| SCHEMBL8580217 | 0.66 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811618-B1 | Furfurylthioalkanes, process for their preparation and use thereof | HAARMANN & REIMER GMBH (DE) | 2002-10-23 | — | — | EP | disclosed |
| EP-0811618-A1 | Furfurylthioalkanes, process for their preparation and use thereof | HAARMANN & REIMER GMBH (DE) | 1997-12-10 | — | — | EP | disclosed |