⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15940374 | 1.00 | — | — | |
| SCHEMBL7591758 | 1.00 | — | — | |
| SCHEMBL17356122 | 0.75 | — | — | |
| SCHEMBL13741840 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL11719737 | 0.71 | — | — | |
| SCHEMBL30878516 | 0.69 | — | — | |
| SCHEMBL6871703 | 0.69 | — | — | |
| SCHEMBL22478684 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL6555443 | 0.69 | — | — | |
| SCHEMBL15710638 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4322957-A1 | METHODS FOR TREATING DRUG AND VACCINE INDUCED IMMUNE THROMBOCYTOPENIA BY ADMINISTERING SPECIFIC COMPOUNDS | Principia Biopharma Inc. (US) | 2024-02-21 | — | — | EP | claimed |
| US-20230158031-A1 | Treatment of Acute Respiratory Distress Syndrome and Other Disorders Involving Cytokine Storm Using BTK Inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2023-05-25 | — | — | US | claimed |
| WO-2022221527-A1 | METHODS FOR TREATING DRUG AND VACCINE INDUCED IMMUNE THROMBOCYTOPENIA BY ADMINISTERING SPECIFIC COMPOUNDS | PRINCIPIA BIOPHARMA, INC. (US) | 2022-10-20 | — | — | WO | claimed |
| US-20260092061-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LTD (GB) | 2026-04-02 | — | — | US | disclosed |
| US-20250276983-A1 | COMPOUNDS AND METHODS FOR MODULATING HER2 | IAMBIC THERAPEUTICS, INC. | 2025-09-04 | — | — | US | disclosed |
| EP-4587126-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | Amphista Therapeutics Ltd (GB) | 2025-07-23 | — | — | EP | disclosed |
| EP-4577549-A1 | COMPOUNDS AND METHODS FOR MODULATING HER2 | Iambic Therapeutics, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| US-20250197402-A1 | Tyrosine Kinase Inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2025-06-19 | — | — | US | disclosed |
| CN-115244055-B | Pyrimidine five-membered ring derivative and application thereof | 江苏先声药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| US-20240182494-A1 | COMPOUNDS AND METHODS FOR MODULATING HER2 | IAMBIC THERAPEUTICS, INC. | 2024-06-06 | — | — | US | disclosed |
| WO-2024057021-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LIMITED (GB) | 2024-03-21 | — | — | WO | disclosed |
| US-20140228358-A1 | ACYCLIC CYANOETHYLPYRAZOLES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-08-14 | — | — | US | disclosed |
| US-20130131039-A1 | 5,7-SUBSTITUTED-IMIDAZO[1,2-C]PYRIMIDINES AS INHIBITORS OF JAK KINASES | ARRAY BIOPHARMA INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131039-A1 | 5,7-SUBSTITUTED-IMIDAZO[1,2-C]PYRIMIDINES AS INHIBITORS OF JAK KINASES | ARRAY BIOPHARMA INC. (US) | 2013-05-23 | — | — | US | disclosed |
| EP-0663394-B1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL CO (JP) | 2002-11-13 | — | — | EP | disclosed |
| EP-0464736-B1 | A process for producing 5-amino-4-halogeno-1H-pyrazole compounds | FUJI PHOTO FILM CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5498725-A | Process for preparing 5-aminodihydropyrrole intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0663394-A1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-07-19 | — | — | EP | disclosed |
| US-5122612-A | PROCESS FOR PRODUCING 5-AMINO-4-HALOGENO-1H-PYRAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| EP-0464736-A1 | A process for producing 5-amino-4-halogeno-1H-pyrazole compounds | Fuji Photo Film Co., Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |