Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CBLB | Q13191 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12168624 | 0.86 | MAPK8 (0.55) | MAPK8CYP1A2BTKMAPTKDM4E | |
| SCHEMBL29683116 | 0.86 | MAPK8 (0.55) | MAPK8CYP1A2BTKMAPTKDM4E | |
| SCHEMBL15746900 | 0.84 | ALDH1A1 (0.43) | MAPK8CYP1A2ALDH1A1MAPTCNR2 | |
| SCHEMBL3924036 | 0.84 | MAPK8 (0.54) | MAPK8CYP1A2BTKMAPTCNR2 | |
| SCHEMBL31471117 | 0.84 | MAPK8 (0.54) | MAPK8CYP1A2BTKALDH1A1MAPT | |
| SCHEMBL21826846 | 0.84 | MAPK8 (0.54) | MAPK8CYP1A2BTKALDH1A1MAPT | |
| SCHEMBL18254259 | 0.83 | MAPK8 (0.56) | MAPK8CYP1A2BTKALDH1A1MAPT | |
| Potassium Ion SCHEMBL28087603 | 0.83 | MAPK8 (0.53) | MAPK8CYP1A2BTKMAPTCNR2 | |
| SCHEMBL1536654 | 0.83 | CYP1A2 (0.74) | MAPK8CYP1A2ALDH1A1MAPTKDM4E | |
| SCHEMBL23463627 | 0.81 | BTK (0.48) | MAPK8CYP1A2BTKALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300900-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-30 | — | — | US | disclosed |
| EP-3810595-A1 | OGA INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2021-04-28 | — | — | EP | disclosed |
| CN-112334462-A | OGA inhibitor compounds | 詹森药业有限公司 | 2021-02-05 | — | — | CN | disclosed |
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
| EP-0885194-B1 | PYRIDYL-PHENYL- AND BENZYLETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES AND FOR CONTROLLING ANIMAL PESTS | BASF AG (DE) | 2002-10-16 | — | — | EP | disclosed |
| US-6114363-A | ACTIVITY AGAINST A BROAD SPECTRUM OF PHYTOPATHOGENIC FUNGI; COMPOUNDS SUCH AS N-METHYL-E-2-METHOXYIMINO-2-((2-(3-CHLORO-5-(PROP-1-EN-3-OXIMINOETH-1' -YL)PYRIDIN-2-YL))OXYMETHYL) PHENYL)ACETAMIDE | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| EP-0885194-A1 | PYRIDYL-PHENYL- AND BENZYLETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES AND FOR CONTROLLING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997030032-A1 | PYRIDYL-PHENYL- AND BENZYLETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES AND FOR CONTROLLING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300900-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | MAPK8 4465/4885CYP1A2 4439/4885BTK 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.