Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.66 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.55 |
| ▸ | PRKCG | P05129 | 2/20 | 0.55 |
| ▸ | PRKCB | P05771 | 2/20 | 0.55 |
| ▸ | PRKCA | P17252 | 2/20 | 0.55 |
| ▸ | PRKCH | P24723 | 2/20 | 0.55 |
| ▸ | PRKCI | P41743 | 2/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.55 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.55 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.55 |
| ▸ | AKT1 | P31749 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666820 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB | |
| SCHEMBL28668717 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB | |
| SCHEMBL14523309 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB | |
| SCHEMBL28688761 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB | |
| SCHEMBL14363934 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB | |
| SCHEMBL11889677 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB | |
| SCHEMBL20851998 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB | |
| SCHEMBL20852013 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB | |
| SCHEMBL20851912 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB | |
| SCHEMBL28679209 | 1.00 | LPAR5 (0.66) | LPAR5P2RY10PRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702556-B1 | (PHOSPHO)LIPIDS FOR COMBATTING HEPATITIS B VIRUS INFECTION | UNIV WAKE FOREST (US) | 2002-10-23 | — | — | EP | claimed |
| US-6030960-A | INHIBITING THE PRODUCTION OF HEPATITIS VIRUS-INDUCED ANTIGENS IN A HUMAN SUBJECT BY ADMINISTERING A COMPOUND | WAKE FOREST UNIVERSITY (US) | 2000-02-29 | — | — | US | claimed |
| US-5770584-A | ADMINISTERING AN ALKYL LIPID OR ALKYL LIPID DERIVATIVE VIRICIDES | WAKE FOREST UNIVERSITY (US) | 1998-06-23 | — | — | US | claimed |
| EP-0702556-A1 | (PHOSPHO)LIPIDS FOR COMBATTING HEPATITIS B VIRUS INFECTION | WAKE FOREST UNIVERSITY (US) | 1996-03-27 | — | — | EP | claimed |
| WO-1994028908-A2 | (PHOSPHO)LIPIDS FOR COMBATTING HEPATITIS B VIRUS INFECTION | WAKE FOREST UNIVERSITY (US) | 1994-12-22 | — | — | WO | claimed |
| US-20070167408-A1 | NOVEL ALKYL PHOSPHOLIPID DERIVATIVES WITH REDUCED CYTOTOXICITY AND USES THEREOF | ZENTARIS GMBH (DE) | 2007-07-19 | — | — | US | disclosed |
| EP-0702556-B1 | (PHOSPHO)LIPIDS FOR COMBATTING HEPATITIS B VIRUS INFECTION | UNIV WAKE FOREST (US) | 2002-10-23 | — | — | EP | disclosed |
| US-6030960-A | INHIBITING THE PRODUCTION OF HEPATITIS VIRUS-INDUCED ANTIGENS IN A HUMAN SUBJECT BY ADMINISTERING A COMPOUND | WAKE FOREST UNIVERSITY (US) | 2000-02-29 | — | — | US | disclosed |
| US-5770584-A | ADMINISTERING AN ALKYL LIPID OR ALKYL LIPID DERIVATIVE VIRICIDES | WAKE FOREST UNIVERSITY (US) | 1998-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167408-A1 | NOVEL ALKYL PHOSPHOLIPID DERIVATIVES WITH REDUCED CYTOTOXICITY AND USES THEREOF | PHOSPHO1, PTDSS1, PTDSS2 | LPAR5 87/4885P2RY10 984/4885PRKD3 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.