Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 13/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593195 | 0.95 | GNRHR (0.37) | GNRHRMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL7596779 | 0.93 | GNRHR (0.43) | GNRHRMEN1KMT2AEDNRB | |
| SCHEMBL7598751 | 0.93 | GNRHR (0.36) | GNRHRMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL7594085 | 0.93 | GNRHR (0.36) | GNRHRMEN1KMT2AALDH1A1EDNRB | |
| SCHEMBL7591509 | 0.93 | GNRHR (0.37) | GNRHRMEN1KMT2AALDH1A1EDNRB | |
| SCHEMBL7598723 | 0.93 | GNRHR (0.36) | GNRHRMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL7593455 | 0.93 | GNRHR (0.36) | GNRHRMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL7594584 | 0.92 | GNRHR (0.36) | GNRHRMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL7593503 | 0.92 | GNRHR (0.33) | GNRHRKCNH2EDNRB | |
| SCHEMBL7597312 | 0.92 | MEN1 (0.36) | GNRHRMEN1KMT2AALDH1A1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846119-B1 | THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE AS ENDOTHELIN ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-11-13 | — | — | EP | disclosed |