1-Methylimidazole

1-Methylimidazole

SCHEMBL7593374

Cn1ccnc1.Cn1cncc1C(O)c1ccc(C#N)c(F)c1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 8/20 0.44
FNTB P49356 8/20 0.44
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
PGGT1B P53609 6/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5094163 0.91 FNTA (0.47) FNTAFNTBCYP11B1CYP11B2PGGT1B
SCHEMBL7568654 0.80 FNTA (0.41) FNTAFNTBPGGT1B
SCHEMBL7571052 0.77 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL7577271 0.77 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL7183607 0.77 FNTA (0.47) FNTAFNTBCYP11B1CYP11B2PGGT1B
SCHEMBL5094152 0.77 FNTA (0.49) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL8165002 0.75 PGGT1B (0.51) FNTAFNTBPGGT1B
SCHEMBL8169080 0.75 PGGT1B (0.48) FNTAFNTBPGGT1B
SCHEMBL7757384 0.75 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL7578956 0.74 FNTA (0.48) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002078702-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2002-10-10 WO disclosed