SCHEMBL7757384

SCHEMBL7757384

Cn1cncc1C(CN)c1ccc(C#N)c(F)c1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 8/20 0.48
FNTB P49356 8/20 0.48
PGGT1B P53609 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7183607 0.85 FNTA (0.47) FNTAFNTBPGGT1B
SCHEMBL5094163 0.82 FNTA (0.47) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL7757577 0.81 FNTA (0.43) FNTAFNTBPGGT1B
SCHEMBL7754508 0.78 FNTA (0.41) FNTAFNTBPGGT1B
SCHEMBL7751663 0.77 FNTA (0.41) FNTAFNTB
SCHEMBL7751658 0.77 FNTA (0.43) FNTAFNTB
Hydrochloric Acid SCHEMBL7755636 0.76 FNTA (0.43) FNTAFNTB
Hydrochloric Acid SCHEMBL7755641 0.76 FNTA (0.41) FNTAFNTB
SCHEMBL8128480 0.76 FNTA (0.42) FNTAFNTB
1-Methylimidazole SCHEMBL7593374 0.75 FNTA (0.44) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001051125-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2001-07-19 WO disclosed
WO-2000034437-A2 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2000-06-15 WO disclosed