Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 4/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597230 | 1.00 | TSHR (0.38) | TSHRTHRBFDPSSMPD1DNM1 | |
| SCHEMBL7597797 | 1.00 | TSHR (0.38) | TSHRTHRBFDPSSMPD1DNM1 | |
| SCHEMBL28181126 | 1.00 | TSHR (0.38) | TSHRTHRBFDPSSMPD1DNM1 | |
| SCHEMBL7596164 | 1.00 | TSHR (0.38) | TSHRTHRBFDPSSMPD1DNM1 | |
| SCHEMBL7601029 | 1.00 | TSHR (0.38) | TSHRTHRBFDPSSMPD1DNM1 | |
| SCHEMBL29027614 | 0.86 | TSHR (0.38) | TSHRTHRBFDPSSMPD1DNM1 | |
| SCHEMBL29027951 | 0.86 | TSHR (0.38) | TSHRTHRBFDPSSMPD1DNM1 | |
| SCHEMBL3001808 | 0.86 | TSHR (0.38) | TSHRTHRBFDPSSMPD1DNM1 | |
| SCHEMBL29027652 | 0.86 | TSHR (0.38) | TSHRTHRBFDPSSMPD1DNM1 | |
| SCHEMBL5622983 | 0.84 | FDPS (0.31) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917465-B1 | ANTIMALARIAL AND ANTI-BABESIOSIS AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AGENTS | VIRBAC SA (FR) | 2002-11-20 | — | — | EP | disclosed |