Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520430 | 0.83 | ESR1 (0.56) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL28334196 | 0.82 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL9846646 | 0.81 | ESR1 (0.58) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL604070 | 0.81 | ESR1 (0.58) | ESR1ESR2CYP3A4BLMALDH1A1 | |
| SCHEMBL9007168 | 0.81 | GAA (0.46) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27794813 | 0.80 | ESR1 (0.53) | ESR1ESR2CYP3A4ALDH1A1HDAC3 | |
| SCHEMBL27872714 | 0.76 | ESR1 (0.51) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL27506091 | 0.72 | ESR1 (0.47) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| Bicarbonate SCHEMBL10882220 | 0.72 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL199439 | 0.71 | ESR1 (0.68) | ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238003-A1 | MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001034694-A1 | MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2001-05-17 | — | — | WO | disclosed |