Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334196 | 0.88 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL604070 | 0.86 | ESR1 (0.58) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL2520430 | 0.85 | ESR1 (0.56) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL27794813 | 0.82 | ESR1 (0.53) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL7593752 | 0.81 | ESR1 (0.51) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL27872714 | 0.81 | ESR1 (0.51) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| Bicarbonate SCHEMBL10882220 | 0.81 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL27506091 | 0.77 | ESR1 (0.47) | ESR1ESR2CYP3A4ALDH1A1HSD17B3 | |
| SCHEMBL312876 | 0.76 | ESR1 (0.68) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL199439 | 0.76 | ESR1 (0.68) | ESR1ESR2CYP3A4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421928-A2 | Hydroxyphenylcarboxylic acid esters as stabilizers | CIBA-GEIGY AG (CH) | 1991-04-10 | — | — | EP | claimed |