Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355970 | 0.84 | ALDH1A1 (0.39) | TSHRFAAH | |
| SCHEMBL7591938 | 0.84 | TSHR (0.34) | TSHRTRPV1CHRM2CHRM4CHRM1 | |
| SCHEMBL5355975 | 0.84 | ALDH1A1 (0.39) | TSHRFAAH | |
| SCHEMBL23779935 | 0.79 | TSHR (0.37) | TSHRTRPV1CHRM2CHRM4CHRM1 | |
| SCHEMBL23779934 | 0.79 | TSHR (0.37) | TSHRTRPV1CHRM2CHRM4CHRM1 | |
| SCHEMBL3143929 | 0.78 | TSHR (0.36) | TSHRTRPV1CHRM2CHRM4CHRM1 | |
| SCHEMBL17169905 | 0.75 | TSHR (0.37) | TSHRTRPV1CHRM2CHRM4CHRM1 | |
| SCHEMBL9194615 | 0.74 | RNPEP (0.38) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL5200741 | 0.74 | TSHR (0.40) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL17164473 | 0.73 | TSHR (0.36) | TSHRTRPV1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| EP-0573289-B1 | Process for preparation of 2-oxo-1-piperidinyl derivatives | BRACCO INT BV (NL) | 1999-04-28 | — | — | EP | disclosed |
| US-5628980-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-05-13 | — | — | US | disclosed |
| US-5614638-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-03-25 | — | — | US | disclosed |
| US-5591846-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. | 1997-01-07 | — | — | US | disclosed |
| US-5559237-A | Process for preparation of 2-oxo-1-piperidinyl derivatives | BRACCO INTERNATIONAL B.V. (NL) | 1996-09-24 | — | — | US | disclosed |
| US-5359077-A | Process for preparation of 2-oxo-1 piperidinyl derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0573289-A2 | Process for preparation of 2-oxo-1-piperidinyl derivatives | BRACCO INTERNATIONAL B.V. (NL) | 1993-12-08 | — | — | EP | disclosed |