Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13220206 | 0.90 | LMNA (0.50) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL7594751 | 0.88 | LMNA (0.46) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL6226822 | 0.88 | LMNA (0.46) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL7587928 | 0.87 | LMNA (0.56) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL7592788 | 0.86 | LMNA (0.44) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL3047183 | 0.86 | LMNA (0.47) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL7595621 | 0.86 | LMNA (0.44) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL7594162 | 0.85 | LMNA (0.50) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL7594734 | 0.85 | LMNA (0.44) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL7592858 | 0.84 | LMNA (0.51) | LMNACYP2C19HIF1ASMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| WO-2000037115-A1 | WATER-SOLUBLE CONTRAST MEDIA FOR X-RAY IMAGING | NYCOMED IMAGING AS (NO) | 2000-06-29 | — | — | WO | disclosed |