Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110369 | 0.84 | CES1 (0.47) | CES1ALDH1A1LMNAHPGDFOLH1 | |
| SCHEMBL9436872 | 0.76 | CES1 (0.54) | CES1ALDH1A1LMNAKMT2A | |
| SCHEMBL29012481 | 0.76 | CES1 (0.53) | CES1ALDH1A1KCNN4CYP2C9HIF1A | |
| SCHEMBL27709505 | 0.74 | CES1 (0.66) | CES1ALDH1A1LMNAHPGDKCNN4 | |
| SCHEMBL8009263 | 0.72 | CES1 (0.64) | CES1ALDH1A1LMNAHPGDKCNN4 | |
| SCHEMBL14174509 | 0.71 | LMNA (0.46) | ALDH1A1LMNAKMT2A | |
| SCHEMBL11221183 | 0.71 | CES1 (0.50) | CES1ALDH1A1CYP2C9HIF1AKDM4E | |
| Methoxymethane SCHEMBL8661498 | 0.71 | LMNA (0.41) | CES1ALDH1A1LMNAHPGDFOLH1 | |
| SCHEMBL30276868 | 0.71 | TAAR1 (0.42) | ALDH1A1MTNR1AMTNR1BTAAR1 | |
| SCHEMBL139732 | 0.71 | TAAR1 (0.42) | ALDH1A1MTNR1AMTNR1BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153948-A1 | Additive functionalized organophilic nano-scaled fillers | CAMENZIND HUGO | 2008-06-26 | — | — | US | disclosed |
| EP-0705865-B1 | Photoinitiators compatible with silicones and photosensitive compositions containing the same | AGFA GEVAERT (BE) | 2002-11-06 | — | — | EP | disclosed |
| EP-0705865-A1 | Photoinitiators compatible with silicones and photosensitive compositions containing the same | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-10 | — | — | EP | disclosed |