SCHEMBL7594347

SCHEMBL7594347

Ic1ccc(-c2cccs2)s1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.52
DPP4 P27487 4/20 0.50
ALDH1A1 P00352 7/20 0.48
KDM4E B2RXH2 7/20 0.48
L3MBTL1 Q9Y468 5/20 0.48
GAA P10253 3/20 0.48
MAPT P10636 3/20 0.48
LMNA P02545 2/20 0.48
GLA P06280 2/20 0.48
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
MEN1 O00255 3/20 0.47
HPGD P15428 3/20 0.47
KMT2A Q03164 3/20 0.47
HSD17B10 Q99714 3/20 0.47
POLB P06746 2/20 0.47
CASP1 P29466 2/20 0.47
CASP7 P55210 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498630 0.98 DPP4 (0.53) LTA4HDPP4ALDH1A1KDM4EL3MBTL1
SCHEMBL2742433 0.83 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EL3MBTL1
SCHEMBL499333 0.83 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EL3MBTL1
SCHEMBL13942801 0.83 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EL3MBTL1
SCHEMBL1105086 0.83 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EL3MBTL1
SCHEMBL23611278 0.83 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EL3MBTL1
Alpha-Terthienyl SCHEMBL147274 0.83 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EL3MBTL1
SCHEMBL14703073 0.83 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EL3MBTL1
SCHEMBL13707354 0.83 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EL3MBTL1
SCHEMBL13707359 0.83 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2762514-B1 COMPOSITION HAVING CHANGEABLE SOLUBILITY, HOLE TRANSPORT MATERIAL COMPOSITION, AND ORGANIC ELECTRONIC ELEMENT PRODUCED USING EACH OF SAID COMPOSITIONS SHOWA DENKO MATERIALS CO LTD (JP) 2021-03-17 EP disclosed
CN-104185803-B Polarized film, optical film, and image display device 日东电工株式会社 2017-05-24 CN disclosed
CN-106661386-A Laminate optical film production method 日东电工株式会社 2017-05-10 CN disclosed
WO-2017073065-A1 NOVEL ANTICANCER DRUG 公益財団法人静岡県産業振興財団 2017-05-04 WO disclosed
US-9263683-B2 Use of cobalt complexes for preparing an active layer in a photovoltaic cell, and corresponding photovoltaic cell CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-02-16 US disclosed
CN-105324240-A Transparent conductive laminated film, method for producing same, and touch panel NITTO DENKO CORP 2016-02-10 CN disclosed
US-9147848-B2 Low bandgap dicyanovinyl and tricyanovinyl oligothiophenes for solar cell applications NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-09-29 US disclosed
US-20150141664-A1 LOW BANDGAP DICYANOVINYL AND TRICYANOVINYL OLIGOTHIOPHENES FOR SOLAR CELL APPLICATIONS NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-05-21 US disclosed
EP-2691404-B1 USE OF COBALT COMPLEXES FOR THE PREPARATION OF THE ACTIVE LAYER OF A PHOTVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL CENTRE NAT RECH SCIENT (FR) 2015-05-06 EP disclosed
US-8975419-B2 Low bandgap dicyanovinyl and tricyanovinyl oligothiophenes for solar cell applications NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-03-10 US disclosed
US-20020114973-A1 Molecular compound, luminous material using the same, and luminous element JAPAN CHEMICAL INNOVATION INSTITUTE (JP) 2002-08-22 US disclosed
US-6355365-B1 FOR USE IN ORGANIC ELECTRO LUMINESCENCE (EL) DEVICE; EFFICIENCY JAPAN CHEMICAL INNOVATION INSTITUTE (JP) 2002-03-12 US disclosed
EP-1007035-A4 POLYTHIOPHENE ANTI-TUMOR AGENTS PURDUE RESEARCH FOUNDATION (US) 2000-11-22 EP disclosed
EP-1007035-A1 POLYTHIOPHENE ANTI-TUMOR AGENTS PURDUE RESEARCH FOUNDATION (US) 2000-06-14 EP disclosed
WO-1998023269-A1 POLYTHIOPHENE ANTI-TUMOR AGENTS PURDUE RESEARCH FOUNDATION (US) 1998-06-04 WO disclosed
US-5753692-A PLANT EXTRACTS, IMMUNOSTIMULANTS TREATING IMMUNODEFICIENCY DISEASES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-19 US disclosed
US-5747525-A ANTITUMOR AGENTS OF OLIGOMERS OF THIOPHENE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-05 US disclosed
US-5741811-A ADMINISTERING TO CANCER PATIENTS PURDUE RESEARCH FOUNDATION (US) 1998-04-21 US disclosed
US-5602170-A ADMINISTERING ANTIIFLAMMATORY AGENT INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1997-02-11 US disclosed
US-5578636-A Polythiophene anti-tumor agents PURDUE RESEARCH FOUNDATION (US) 1996-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141664-A1 LOW BANDGAP DICYANOVINYL AND TRICYANOVINYL OLIGOTHIOPHENES FOR SOLAR CELL APPLICATIONS DSG1, CDC73, CDC23 LTA4H 3894/4885DPP4 1416/4885ALDH1A1 3139/4885
US-20020114973-A1 Molecular compound, luminous material using the same, and luminous element TYR, BRD4, NOTCH1 LTA4H 653/4885DPP4 3917/4885ALDH1A1 2963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.