SCHEMBL7594486

SCHEMBL7594486

C1=CC(COc2ccccc2)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.46
TDP1 Q9NUW8 1/20 0.42
KCNA3 P22001 2/20 0.38
SIGMAR1 Q99720 2/20 0.36
HTR2A P28223 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RECQL P46063 1/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9315861 0.79 KCNA3 (0.48) HTR6KCNA3TAAR1ALDH1A1RECQL
SCHEMBL7595592 0.78 HTR6 (0.49) HTR6SIGMAR1HTR2ASLC6A2SLC6A3
SCHEMBL8570811 0.78 HTR6 (0.49) HTR6SIGMAR1HTR2ASLC6A2SLC6A3
SCHEMBL13278806 0.78 HTR6 (0.49) HTR6SIGMAR1HTR2ASLC6A2SLC6A3
Hydrochloric Acid SCHEMBL6942508 0.76 HTR6 (0.47) HTR6SIGMAR1HTR2ASLC6A2SLC6A3
Hydrochloric Acid SCHEMBL4366219 0.76 HTR6 (0.47) HTR6SIGMAR1HTR2ASLC6A2SLC6A3
SCHEMBL1453509 0.76 HTR6 (0.58) HTR6SIGMAR1HTR2AALDH1A1SLC6A2
SCHEMBL668105 0.74 HTR6 (0.56) HTR6SIGMAR1HTR2ASLC6A2SLC6A3
SCHEMBL9859810 0.74 HTR6 (0.56) HTR6SIGMAR1HTR2ASLC6A2SLC6A3
SCHEMBL4366224 0.74 HTR6 (0.45) HTR6SIGMAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543310-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN disclosed
CN-103626895-B For catalyst component and the method for preparing catalyst thereof of olefinic polyreaction SINOPEC CORP. (CN) 2016-03-30 CN disclosed
CN-103626893-B For catalyst component and the method for preparing catalyst thereof of olefinic polyreaction SINOPEC CORP. (CN) 2016-03-30 CN disclosed
CN-103626896-B For catalyst component and the method for preparing catalyst thereof of olefinic polyreaction SINOPEC CORP. (CN) 2016-03-30 CN disclosed
CN-103626894-B For catalyst component and the method for preparing catalyst thereof of olefinic polyreaction SINOPEC CORP. (CN) 2016-03-30 CN disclosed
CN-103626893-A Catalyst component for alkene polymerization reactions and preparation method of catalyst prepared from the catalyst component CHINA PETROLEUM & CHEMICAL 2014-03-12 CN disclosed
CN-103626895-A Catalyst component for alkene polymerization reactions and preparation method of catalyst thereof CHINA PETROLEUM & CHEMICAL 2014-03-12 CN disclosed
CN-103626894-A Catalyst component for alkene polymerization reaction and preparation method of catalyst thereof CHINA PETROLEUM & CHEMICAL 2014-03-12 CN disclosed
EP-1260523-B1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORP (CN) 2013-01-23 EP disclosed
CN-1289451-C Diethers suitable for use in the preparation of ziegler-natta catalysts BASEL POLELEFINE ITALY S P A (IT) 2006-12-13 CN disclosed
CN-1210243-C Synthesis method of diether BASEL NORTH AMERICA CO LTD (US) 2005-07-13 CN disclosed
CN-1491929-A Diethers suitable for use in the preparation of ziegler-natta catalysts 2004-04-28 CN disclosed
CN-1473809-A Diethers suitable for use in the preparation of ziegler-natta catalysts ��������ϩ����������޹�˾ 2004-02-11 CN disclosed
CN-1121368-C Diethers suitable for use in the preparation of ziegler-natta catalysts MONTELL NORTH AMERICA INC (US) 2003-09-17 CN disclosed
EP-1260523-A1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORPORATION (CN) 2002-11-27 EP disclosed
CN-1092670-C Process for producing solid catalyst component for olefin polymerization MONTELL NORTH AMERICA INC (US) 2002-10-16 CN disclosed
CN-1090194-C Components, catalysts and processes for the polymerization of olefins BASSEL TECHNOLOGY B V (NL) 2002-09-04 CN disclosed
CN-1143651-A Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1997-02-26 CN disclosed
CN-1141285-A Diethers suitable for use in the preparation of ziegler-natta catalysts MONTELL NORTH AMERICA INC (US) 1997-01-29 CN disclosed
CN-1141303-A Process for producing solid catalyst component for olefin polymerization MONTELL NORTH AMERICA INC (US) 1997-01-29 CN disclosed