Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594493 | 1.00 | CHRNB2 (0.40) | CHRNB2CHRNA4 | |
| SCHEMBL5174095 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL5174090 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL7228431 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL5174959 | 0.76 | AAK1 (0.44) | — | |
| SCHEMBL2889610 | 0.74 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL24687082 | 0.74 | NQO1 (0.54) | CHRNB2CHRNA4 | |
| SCHEMBL5173626 | 0.73 | CHRNB2 (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL5173631 | 0.73 | CHRNB2 (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL5172747 | 0.73 | CHRNB2 (0.43) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257535-A1 | SUBSTITUTED PYRIDINE COMPOUNDS USEFUL FOR CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001056991-A1 | SUBSTITUTED PYRIDINE COMPOUNDS USEFUL FOR CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 2001-08-09 | — | — | WO | disclosed |