Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595077 | 0.91 | CYSLTR2 (0.52) | ALOX5APGPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL8688616 | 0.83 | CYSLTR1 (0.52) | ALOX5APGPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL7598790 | 0.80 | CYSLTR1 (0.56) | ALOX5APGPBAR1CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL7592902 | 0.79 | GPBAR1 (0.64) | ALOX5APGPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL8645138 | 0.78 | GPBAR1 (0.59) | ALOX5APGPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL7596624 | 0.78 | CYSLTR1 (0.68) | ALOX5APGPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL7596636 | 0.77 | ALOX5 (0.44) | ALOX5APGPBAR1CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL8688436 | 0.77 | CYSLTR1 (0.59) | ALOX5APGPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL8842339 | 0.77 | CYSLTR1 (0.53) | ALOX5APGPBAR1CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL7592647 | 0.76 | GPBAR1 (0.54) | ALOX5APGPBAR1CYSLTR1CYSLTR2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862557-B1 | SYMMETRICAL bis-HETEROARYLMETHOXYPHENYLALKYL CARBOXYLATES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LAB (US) | 2002-11-27 | — | — | EP | disclosed |