SCHEMBL7594684

SCHEMBL7594684

CO[C@H]1O[C@H](C(O)Cc2ccccc2)[C@](O)(Cc2ccc(Cl)cc2)[C@@](O)(Cc2ccc(Br)cc2)[C@]1(O)Cc1ccc(I)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643397 0.85 HTT (0.34)
SCHEMBL5983969 0.85 HTT (0.34)
SCHEMBL7569063 0.80 PPARG (0.35) PPARGPPARA
SCHEMBL7563870 0.79 PPARG (0.32) PPARGPPARA
SCHEMBL6891299 0.77
SCHEMBL6883876 0.77
SCHEMBL9192197 0.77
SCHEMBL7565489 0.74 PPARG (0.33) PPARGPPARA
SCHEMBL11100069 0.73
SCHEMBL7566181 0.73 MEN1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233970-A2 PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-08-28 EP disclosed
WO-2001038337-A2 PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-05-31 WO disclosed