Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.33 |
| ▸ | PPARA | Q07869 | 7/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569063 | 0.95 | PPARG (0.35) | PPARGPPARA | |
| SCHEMBL7645453 | 0.82 | TRPA1 (0.32) | HTT | |
| SCHEMBL6637475 | 0.77 | GRIN2D (0.32) | HTTGRIN2DGRIN3BADRA1DADRA1A | |
| SCHEMBL6895515 | 0.77 | NPC1 (0.33) | HTT | |
| SCHEMBL6895512 | 0.77 | NPC1 (0.33) | HTT | |
| SCHEMBL31016265 | 0.76 | GRIN2D (0.33) | HTTGRIN2DGRIN3BADRA1DADRA1A | |
| SCHEMBL3163944 | 0.76 | GRIN2D (0.33) | HTTGRIN2DGRIN3BADRA1DADRA1A | |
| SCHEMBL3136547 | 0.76 | GRIN2D (0.33) | HTTGRIN2DGRIN3BADRA1DADRA1A | |
| SCHEMBL3155159 | 0.76 | GRIN2D (0.33) | HTTGRIN2DGRIN3BADRA1DADRA1A | |
| SCHEMBL3145397 | 0.76 | GRIN2D (0.33) | HTTGRIN2DGRIN3BADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233970-A2 | PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001038337-A2 | PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-31 | — | — | WO | disclosed |