Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401266 | 0.85 | ALDH1A1 (0.51) | LMNAMAPK1PTGS1SMN1; SMN2KDM4E | |
| SCHEMBL6401263 | 0.85 | ALDH1A1 (0.51) | LMNAMAPK1PTGS1SMN1; SMN2KDM4E | |
| SCHEMBL6401264 | 0.85 | ALDH1A1 (0.51) | LMNAMAPK1PTGS1SMN1; SMN2KDM4E | |
| SCHEMBL5494784 | 0.83 | KMT2A (0.64) | LMNAMAPK1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL23972905 | 0.81 | CTSA (0.48) | LMNAMAPK1PTGS1SMN1; SMN2KMT2A | |
| SCHEMBL6397562 | 0.81 | ALDH1A1 (0.53) | LMNAMAPK1PTGS1SMN1; SMN2KMT2A | |
| SCHEMBL6397561 | 0.81 | ALDH1A1 (0.53) | LMNAMAPK1PTGS1SMN1; SMN2KMT2A | |
| SCHEMBL6397566 | 0.81 | ALDH1A1 (0.53) | LMNAMAPK1PTGS1SMN1; SMN2KMT2A | |
| SCHEMBL5494789 | 0.79 | PTGS1 (0.68) | LMNAMAPK1PTGS1KMT2A | |
| SCHEMBL10831605 | 0.79 | PTGS1 (0.68) | LMNAMAPK1PTGS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259211-A1 | DUAL COMPOSITION COSMETIC PRODUCT WITH A CONCENTRATION SENSITIVE AND AN INCOMPATIBLE ACTIVE RESPECTIVELY PLACED WITHIN FIRST AND SECOND COMPOSITIONS | UNILEVER PLC (GB) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001070188-A1 | LOW pH HIGH FATTY ACID VANISHING CREAM | UNILEVER PLC (GB) | 2001-09-27 | — | — | WO | disclosed |
| WO-2001064166-A1 | DUAL COMPOSITION COSMETIC PRODUCT WITH A CONCENTRATION SENSITIVE AND AN INCOMPATIBLE ACTIVE RESPECTIVELY PLACED WITHIN FIRST AND SECOND COMPOSITIONS | UNILEVER PLC (GB) | 2001-09-07 | — | — | WO | disclosed |