SCHEMBL7595039

SCHEMBL7595039

O=C(O)NC1=NN(c2ccccc2)C(=O)C1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.78
KMT2A Q03164 8/20 0.78
GAA P10253 10/20 0.72
GRK5 P34947 1/20 0.71
CDK8 P49336 1/20 0.71
L3MBTL1 Q9Y468 3/20 0.70
POLB P06746 2/20 0.70
RECQL P46063 2/20 0.70
BLM P54132 1/20 0.70
MAPT P10636 7/20 0.67
ALDH1A1 P00352 3/20 0.67
TDP1 Q9NUW8 3/20 0.58
KDM4E B2RXH2 2/20 0.58
USP2 O75604 1/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
CHRM2 P08172 1/20 0.58
CYP3A4 P08684 1/20 0.58
CHRM1 P11229 1/20 0.58
TSHR P16473 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3259543 0.88 MEN1 (1.00) MEN1KMT2AGAAGRK5CDK8
SCHEMBL124737 0.86 MEN1 (0.72) MEN1KMT2AGAAGRK5CDK8
SCHEMBL11863473 0.84 MEN1 (0.72) MEN1KMT2AGAAGRK5CDK8
SCHEMBL124503 0.84 GAA (0.70) MEN1KMT2AGAAGRK5CDK8
SCHEMBL11870457 0.83 MEN1 (0.67) MEN1KMT2AGAAGRK5CDK8
SCHEMBL9093455 0.83 GAA (1.00) MEN1KMT2AGAAGRK5CDK8
SCHEMBL8261088 0.80 MEN1 (0.68) MEN1KMT2AGAAGRK5CDK8
SCHEMBL6757713 0.80 MEN1 (0.63) MEN1KMT2AGAAGRK5CDK8
SCHEMBL11874571 0.79 GAA (0.74) MEN1KMT2AGAAGRK5CDK8
SCHEMBL14256481 0.76 MEN1 (0.62) MEN1KMT2AGAAGRK5CDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1093416-B1 HEAT AND RADIATION-SENSITIVE IMAGING MEDIUM POLAROID CORP (US) 2002-09-18 EP disclosed
US-6258505-B1 WEB WITH ALTERNATING PANELS POLAROID CORPORATION 2001-07-10 US disclosed
EP-1093416-A1 HEAT AND RADIATION-SENSITIVE IMAGING MEDIUM POLAROID CORPORATION (US) 2001-04-25 EP disclosed
US-6054246-A HEATING A COLOR CHANGE LAYER OF COLOR-FORMING REAGENTS TO CAUSE A COLOR CHANGE OF THE LAYER, EXPOSING TO ACTINIC RADIATION TO DEACTIVATE IT, PREVENTING FURTHER THERMAL COLOR CHANGE; DETACHES UPON HEATING BELOW COLOR CHANGE TEMPERATURE POLAROID CORPORATION (US) 2000-04-25 US disclosed
WO-2000001537-A1 HEAT AND RADIATION-SENSITIVE IMAGING MEDIUM POLAROID CORPORATION (US) 2000-01-13 WO disclosed