Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.72 |
| ▸ | GAA | P10253 | 10/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | GRK5 | P34947 | 1/20 | 0.62 |
| ▸ | CDK8 | P49336 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595039 | 0.86 | MEN1 (0.78) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL6514530 | 0.84 | KMT2A (0.56) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL10875014 | 0.80 | MEN1 (0.68) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL11863473 | 0.80 | MEN1 (0.72) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL124503 | 0.80 | GAA (0.70) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL11508671 | 0.78 | MEN1 (0.57) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL11870457 | 0.77 | MEN1 (0.67) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL6757713 | 0.76 | MEN1 (0.63) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL8261088 | 0.76 | MEN1 (0.68) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL13868475 | 0.76 | TYMS (0.55) | MEN1KMT2AGAAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | INCENP, CYBA, ADCY5 | MEN1 4480/4885KMT2A 3041/4885GAA 2311/4885 |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | INCENP, CYBA, PAICS | MEN1 4473/4885KMT2A 2961/4885GAA 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.