Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 8/20 | 0.41 |
| ▸ | HTR1A | P08908 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | DRD1 | P21728 | 3/20 | 0.41 |
| ▸ | DRD5 | P21918 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093710 | 0.87 | GAA (0.51) | GAAMAPTDRD3DRD2HTR1A | |
| SCHEMBL7095695 | 0.85 | GAA (0.53) | GAAMAPTDRD3DRD2HTR1A | |
| SCHEMBL7096669 | 0.84 | GAA (0.53) | GAAMAPTDRD3DRD2HTR1A | |
| SCHEMBL7095622 | 0.82 | GAA (0.55) | GAAMAPTDRD3DRD2HTR1A | |
| SCHEMBL7094815 | 0.81 | GAA (0.60) | GAAMAPTDRD3DRD2FAAH | |
| SCHEMBL7094842 | 0.80 | DRD2 (0.54) | GAAMAPTDRD3DRD2HTR1A | |
| SCHEMBL7094839 | 0.79 | GAA (0.63) | GAAMAPTDRD3DRD2FAAH | |
| SCHEMBL7094781 | 0.78 | GAA (0.59) | GAAMAPTDRD3DRD2FAAH | |
| SCHEMBL7095084 | 0.77 | GAA (0.61) | GAAMAPTDRD3DRD2FAAH | |
| SCHEMBL7090741 | 0.75 | GAA (0.64) | GAAMAPTDRD3DRD2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246818-A1 | NOVEL INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2002-10-09 | — | — | EP | claimed |
| WO-2001049680-A1 | NOVEL INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2001-07-12 | — | — | WO | claimed |