SCHEMBL7595192

SCHEMBL7595192

CCOC(=O)C1=C(N)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9548196 0.83 KDM4E (0.72)
SCHEMBL3456275 0.79 MAPT (0.47)
SCHEMBL1144592 0.79 ALDH1A1 (0.47)
SCHEMBL17629580 0.79 KDM4E (0.51)
SCHEMBL5608026 0.78 KDM4E (0.59)
Hydrochloric Acid SCHEMBL7360757 0.78 MAPT (0.46)
SCHEMBL14079850 0.78 ALDH1A1 (0.46)
SCHEMBL21847505 0.78 MAPT (0.46)
SCHEMBL7588914 0.77 KDM4E (0.59)
SCHEMBL15247080 0.77 KDM4E (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0533832-B1 TREATMENT OF MOOD DISORDERS WITH FUNCTIONAL ANTAGONISTS OF THE GLYCINE/NMDA RECEPTOR COMPLEX US SECRETARY UNITED STATES DEP (US) 2002-11-20 EP disclosed
EP-0533832-A4 TREATMENT OF MOOD DISORDERS WITH FUNCTIONAL ANTAGONISTS OF THE GLYCINE/NMDA RECEPTOR COMPLEX US COMMERCE (US) 1993-04-28 EP disclosed
EP-0533832-A1 TREATMENT OF MOOD DISORDERS WITH FUNCTIONAL ANTAGONISTS OF THE GLYCINE/NMDA RECEPTOR COMPLEX THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1993-03-31 EP disclosed
US-5086072-A TREATMENT OF MOOD DISORDERS WITH FUNCTIONAL ANTAGONISTS OF THE GLYCINE/NMDA RECEPTOR COMPLEX THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1992-02-04 US disclosed
WO-1991019493-A1 TREATMENT OF MOOD DISORDERS WITH FUNCTIONAL ANTAGONISTS OF THE GLYCINE/NMDA RECEPTOR COMPLEX THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1991-12-26 WO disclosed