Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12425710 | 1.00 | HSD17B3 (0.52) | HSD17B3ALDH1A1PKMSLC6A19BACE1 | |
| SCHEMBL1419505 | 0.82 | HSD17B3 (0.46) | HSD17B3ALDH1A1PKMSLC6A19BACE1 | |
| SCHEMBL12175516 | 0.82 | HSD17B3 (0.53) | HSD17B3ALDH1A1PKMSLC6A19BACE1 | |
| SCHEMBL8900441 | 0.80 | HSD17B3 (0.65) | HSD17B3ALDH1A1PKMSLC6A19BACE1 | |
| SCHEMBL709614 | 0.80 | HSD17B3 (0.65) | HSD17B3ALDH1A1PKMSLC6A19BACE1 | |
| SCHEMBL699462 | 0.80 | HSD17B3 (0.65) | HSD17B3ALDH1A1PKMSLC6A19BACE1 | |
| SCHEMBL256054 | 0.80 | SLC6A19 (0.53) | HSD17B3ALDH1A1PKMSLC6A19BACE1 | |
| SCHEMBL4084847 | 0.80 | HSD17B3 (0.56) | HSD17B3ALDH1A1PKMSLC6A19BACE1 | |
| SCHEMBL14416285 | 0.80 | SLC6A19 (0.53) | HSD17B3ALDH1A1PKMSLC6A19BACE1 | |
| SCHEMBL10901886 | 0.80 | HSD17B3 (0.52) | HSD17B3ALDH1A1PKMSLC6A19BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257528-A1 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060786-A1 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |