Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107553 | 0.85 | P2RX4 (0.48) | P2RX4MEN1ALDH1A1MAPTKMT2A | |
| Acetic Acid SCHEMBL10626222 | 0.77 | P2RX4 (0.47) | P2RX4MEN1MAPTKMT2ACYP2C9 | |
| Acetone SCHEMBL28309933 | 0.74 | P2RX4 (0.47) | P2RX4MEN1MAPTKMT2AGAA | |
| SCHEMBL66413 | 0.74 | TP53 (0.50) | ALDH1A1 | |
| SCHEMBL9168343 | 0.73 | P2RX4 (0.45) | P2RX4ALDH1A1KMT2ACYP2C9GAA | |
| SCHEMBL2702324 | 0.72 | CYP2D6 (0.48) | ALDH1A1MAPTKMT2APTGS2CYP2D6 | |
| SCHEMBL28488032 | 0.72 | PTGS1 (0.61) | MEN1ALDH1A1MAPTKMT2APTGS2 | |
| Water SCHEMBL8870694 | 0.71 | TP53 (0.47) | — | |
| Methyl Alcohol SCHEMBL6839603 | 0.71 | — | — | |
| Benzene SCHEMBL27883658 | 0.71 | MAOA (0.53) | P2RX4ALDH1A1CYP2C9GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002098408-A1 | PTPASE INHIBITORS FOR IMPROVING CARDIOVASCULAR RISK PROFILE | WYETH (US) | 2002-12-12 | — | — | WO | disclosed |
| WO-2002098407-A1 | COMBINATION OF A PTPase INHIBITOR AND AN ALPHA-GLUCOSIDASE INHIBITOR | WYETH (US) | 2002-12-12 | — | — | WO | disclosed |
| WO-2002098414-A1 | METHODS USING PTPASE INHIBITORS AND INSULIN | WYETH (US) | 2002-12-12 | — | — | WO | disclosed |